Near-infrared and Short-wavelength Autofluorescence in Resolved Central Serous Chorioretinopathy: Association With Outer Retinal Layer Abnormalities

Progressive Loss of Retinal Ganglion Cell Function Precedes Structural Loss by Several Years in Glaucoma Suspects

Structure and Clinical Significance of Central Optic Disc Pits

Enhanced Depth Imaging Optical Coherence Tomography of Optic Nerve Head Drusen

Ability of Cirrus High-Definition Spectral-Domain Optical Coherence Tomography Clock-Hour, Deviation, and Thickness Maps in Detecting Photographic Retinal Nerve Fiber Layer Abnormalities

Anterior Chamber Angle Imaging with Swept-Source Optical Coherence Tomography: Measuring Peripheral Anterior Synechia in Glaucoma

Relating Retinal Nerve Fiber Layer Thickness and Functional Estimates of Ganglion Cell Sampling Density in Healthy Eyes and in Early Glaucoma

Ophthalmic Evaluations in Clinical Studies of Fingolimod (FTY720) in Multiple Sclerosis

Enhancement of Lamina Cribrosa Visibility in Optical Coherence Tomography Images Using Adaptive Compensation

Optic neuritis interferes with optical coherence tomography and magnetic resonance imaging correlations

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All Articles

1. Near-infrared and Short-wavelength Autofluorescence in Resolved Central Serous Chorioretinopathy: Association With Outer Retinal Layer Abnormalities Explore American Journal of Ophthalmology (Apr 17 2013) Journal Articles Purpose: To evaluate the correlation between changes in fundus autofluorescence (AF) measured using 2 different sources (near-infrared fundus autofluorescence from melanin and short-wavelength fundus autofluorescence from lipofuscin) with changes in spectral-domain optical coherence tomography (SD OCT) and fluorescein angiography in resolved central serous chorioretinopathy (CSC).Design: Retrospective, observational case study ... (Read Full Article)

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2. Macular Hole Surgery in Patients with End-stage Choroideremia Explore Ophthalmology (Apr 4 2013) Journal Articles Objective: To assess macular hole surgery in patients with end-stage choroideremia with regard to anatomic closure and visual outcome.Design: Retrospective, interventional case series.Participants: Thirty adult male patients with a diagnosis of advanced choroideremia were reviewed and underwent spectral domain optical coherence tomography (OCT) as part of the screening ... (Read Full Article)

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3. 4D dynamic imaging of the eye using ultrahigh speed SS-OCT Explore Conference Proceedings (Apr 1 2013) Recent advances in swept-source / Fourier domain optical coherence tomography (SS-OCT) technology enable in vivo ultrahigh speed imaging, offering a promising technique for four-dimensional (4-D) imaging of the eye. Using an ultrahigh speed tunable vertical cavity surface emitting laser (VCSEL) light source based SS-OCT prototype system, we performed imaging of human ... (Read Full Article)

   Comment Mentions:   Duker, Jay S. MD   Fujimoto, James G. PhD

4. Optic neuritis interferes with optical coherence tomography and magnetic resonance imaging correlations Explore Multiple Sclerosis (Apr 1 2013) Journal Articles Background: Retinal nerve fibre layer (RNFL) thinning is associated with brain atrophy in multiple sclerosis (MS). An influence of optic neuritis is well documented but sparsely investigated. Recently, the retinal ganglion cell layer (GCL) has been shown to provide superior information regarding visual function and retinal neurodegeneration as compared with ... (Read Full Article)

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5. Foveal Thickness in Healthy Fellow Eyes of Patients With Unilateral Macular Holes Explore American Journal of Ophthalmology (Mar 28 2013) Journal Articles Purpose: To compare the morphologic parameters of ophthalmoscopically and tomographically normal foveae of the fellow eyes of patients with a unilateral macular hole (MH), other unilateral retinal diseases, and healthy eyes.Design: Observational, cross-sectional study.Methods: Of the 849 subjects studied, 183 eyes were excluded because they had an abnormal ... (Read Full Article)

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6. Anatomic Features and Function of the Macula and Outcome of Surgical Tenotomy and Reattachment in Achiasma Explore Ophthalmology (Mar 28 2013) Journal Articles Objective: To examine the anatomic features and function of the macula in achiasma and to compare visual acuity, eye movements, foveation, and eye velocity before and after tenotomy and reattachment (T&R) surgery. Design: Case series. Participants: Two children with isolated achiasma. Methods: Ophthalmologic examinations, brain magnetic resonance imaging, full-field ... (Read Full Article)

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7. Ability of Cirrus High-Definition Spectral-Domain Optical Coherence Tomography Clock-Hour, Deviation, and Thickness Maps in Detecting Photographic Retinal Nerve Fiber Layer Abnormalities Explore Ophthalmology (Mar 28 2013) Journal Articles Purpose: To investigate the ability of clock-hour, deviation, and thickness maps of Cirrus high-definition spectral-domain optical coherence tomography (HD-OCT) in detecting retinal nerve fiber layer (RNFL) defects identified in red-free fundus photographs in eyes with early glaucoma (mean deviation >–6.0 dB). Design: Cross-sectional study. Participants: Two hundred ninety-five eyes ... (Read Full Article)

   Comment Mentions:   Cirrus HD-OCT

8. Glaucoma Detection Ability of Ganglion Cell-Inner Plexiform Layer Thickness by Spectral-Domain Optical Coherence Tomography in High Myopia Explore iovs.org (Mar 28 2013) Journal Articles Purpose. To compare the glaucoma detection ability of macular ganglion cell-inner plexiform layer (GCIPL) thickness measured with Cirrus spectral-domain optical coherence tomography (SD-OCT) with that of peripapillary retinal nerve fiber layer (RNFL) thickness in high myopia. Methods. In 49 highly myopic and 54 nonhighly myopic glaucoma patients—along with 78 ... (Read Full Article)

   Comment Mentions:   Cirrus HD-OCT

9. Progressive Loss of Retinal Ganglion Cell Function Precedes Structural Loss by Several Years in Glaucoma Suspects Explore iovs.org (Mar 28 2013) Journal Articles Purpose. We determined the time lag between loss of retinal ganglion cell function and retinal nerve fiber layer (RNFL) thickness. Methods. Glaucoma suspects were followed for at least four years. Patients underwent pattern electroretinography (PERG), optical coherence tomography (OCT) of the RNFL, and standard automated perimetry testing at 6-month intervals ... (Read Full Article)

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10. Corneal decompensation and angle-closure glaucoma after upside-down implantation of an angle-supported anterior chamber phakic intraocular lens Explore Journal of Cataract & Refractive Surgery (Mar 27 2013) Journal Articles We present the case of a 27-year-old man with severe pain, loss of visual acuity, corneal edema, and high intraocular pressure (IOP) in 1 eye after bilateral Acrysof Cachet phakic intraocular lens (pIOL) implantation. Slitlamp examination was limited due to severe corneal edema, but anterior segment optical coherence tomography indicated ... (Read Full Article)

    Comment Mentions:   Carl Zeiss Meditec

11. Relating Retinal Nerve Fiber Layer Thickness and Functional Estimates of Ganglion Cell Sampling Density in Healthy Eyes and in Early Glaucoma Explore iovs.org (Mar 27 2013) Journal Articles Purpose. To investigate the relationship between retinal nerve fiber layer (RNFL) thickness and peripheral grating resolution acuity (PGRA) as well as differential light sensitivity (DLS) in healthy subjects and patients with early glaucoma. The agreement between estimates of retinal ganglion cell (GC) density from each functional test is explored. Methods ... (Read Full Article)

    Comment Mentions:   Stratus OCT

12. Enhancement of Lamina Cribrosa Visibility in Optical Coherence Tomography Images Using Adaptive Compensation Explore iovs.org (Mar 27 2013) Journal Articles Purpose. We improved the visibility of the lamina cribrosa (LC), including its posterior boundary, in optical coherence tomography (OCT) images of the human optic nerve head (ONH). Methods. An adaptive compensation algorithm was developed to overcome a limitation of our standard compensation algorithm, that is the overamplification of noise at ... (Read Full Article)

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13. Anterior Chamber Angle Imaging with Swept-Source Optical Coherence Tomography: Measuring Peripheral Anterior Synechia in Glaucoma Explore Ophthalmology (Mar 24 2013) Journal Articles Objective: To investigate the use of swept-source optical coherence tomography (OCT) for measuring the area and degree of peripheral anterior synechia (PAS) involvement in patients with angle-closure glaucoma. Design: Cross-sectional study. Participants: Twenty-three eyes with PAS (detected by indentation gonioscopy) from 20 patients with angle-closure glaucoma (20 eyes had primary ... (Read Full Article)

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14. Structure and Clinical Significance of Central Optic Disc Pits Explore Ophthalmology (Mar 24 2013) Journal Articles Objective: To assess the structure of central optic disc pits (ODPs) using enhanced-depth imaging optical coherence tomography (EDI OCT) and to ascertain their clinical significance. Design: Prospective, cross-sectional study. Participants: Patients with an ophthalmoscopically visible central ODP in either eye, irrespective of accompanying ocular disease, were enrolled from the neuro-ophthalmology ... (Read Full Article)

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15. Enhanced Depth Imaging Optical Coherence Tomography of Optic Nerve Head Drusen Explore Ophthalmology (Mar 24 2013) Journal Articles Objective: To assess the value of enhanced depth imaging optical coherence tomography (EDI OCT) in diagnosing and evaluating optic nerve head drusen (ONHD) compared with conventional diagnostic methods. Design: Prospective, comparative, cross-sectional study. Participants: Thirty-four patients with clinically visible or suspected ONHD in either eye based on dilated optic disc ... (Read Full Article)

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16. Ophthalmic Evaluations in Clinical Studies of Fingolimod (FTY720) in Multiple Sclerosis Explore Ophthalmology (Mar 24 2013) Journal Articles Purpose: To report outcomes of ophthalmic evaluations in clinical studies of patients receiving fingolimod (Gilenya; Novartis Pharma AG, Basel, Switzerland) for multiple sclerosis (MS). Design: Analysis done on pooled safety data (N = 2615, all studies group) from 3 double-masked, randomized, parallel-group clinical trials (phase 2 core and extension >5 years ... (Read Full Article)

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17. Dynamic Positional Change and Defocus Curve of a Phakic Foldable Anterior-Chamber Angle-Supported Intraocular Lens during Accommodation Explore Ophthalmology (Mar 20 2013) Journal Articles Objective: To evaluate movements of an anterior-chamber angle-supported phakic intraocular lens (PIOL) Cachet (Alcon, Fort Worth, Texas) and their influence on visual acuity during accommodation. Design: Prospective case series. Participants: We included 54 eyes of 27 patients (15 female, 12 male; age, 38±7.61 years; preoperative manifest spherical equivalent ... (Read Full Article)

    Comment Mentions:   Carl Zeiss Meditec   Visante omni

18. Morphologic Characteristics of Optic Nerve Head Drusen on Spectral-Domain Optical Coherence Tomography Explore American Journal of Ophthalmology (Mar 19 2013) Journal Articles Purpose: To evaluate the morphologic characteristics of optic nerve head drusen.Design: Retrospective case series.Methods: Setting: Institutional (Seoul National University Bundang Hospital). Patients: Sixty-one patients with optic nerve head drusen. Observation procedure: Visible and buried optic nerve head drusen were identified using funduscopy, whereas homogenous and nonhomogenous optic nerve ... (Read Full Article)

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19. Choroidal Thickness in Fellow Eyes of Patients with Acute Primary Angle-Closure Measured by Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography Explore iovs.org (Mar 19 2013) Journal Articles Purpose. We evaluated choroidal thickness in the fellow eyes of patients with acute primary angle-closure (APAC) and compared findings to those of normal controls. Methods. The study group comprised 44 fellow eyes defined as primary angle-closure suspect (PACS) of 44 subjects who had experienced APAC and 43 eyes of 43 ... (Read Full Article)

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20. Microstructure of Parapapillary Atrophy: Beta Zone and Gamma Zone Explore iovs.org (Mar 19 2013) Journal Articles Purpose. To examine the morphologic features of parapapillary atrophy by using enhanced depth imaging optical coherence tomography (EDI-OCT) and color fundus photographs. Methods. The clinical observational comparative study included 80 normal eyes of 46 subjects and 80 eyes of 46 patients with primary open-angle glaucoma. Both groups did not vary ... (Read Full Article)

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21. Anterior segment variations after posterior chamber phakic intraocular lens implantation in myopic eyes Explore Journal of Cataract & Refractive Surgery (Mar 17 2013) Journal Articles Purpose: To evaluate anterior segment variations after posterior chamber phakic intraocular lens (pIOL) implantation in myopic eyes.Setting: Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.Design: Cohort study.Methods: Patients with high myopia were scheduled for nontoric Implantable Collamer Lens pIOL or toric Implantable Collamer Lens pIOL implantation. Anterior ... (Read Full Article)

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22. Usefulness of Macular Thickness Derived from Spectral-Domain Optical Coherence Tomography in the Detection of Glaucoma Progression Explore iovs.org (Mar 15 2013) Journal Articles Purpose. To assess the reproducibility of circumpapillary retinal nerve fiber layer thickness (cRNFLT) and total macular thickness (TMT) parameters using Cirrus spectral domain optical coherence tomography (SD-OCT) and to apply this information to investigate its ability to detect cases where visual field (VF) progression was noted on event-based analysis in ... (Read Full Article)

    Comment Mentions:   Cirrus HD-OCT

23. Influence of the Eye-Tracking-Based Follow-Up Function in Retinal Nerve Fiber Layer Thickness Using Fourier-Domain Optical Coherence Tomography Explore iovs.org (Mar 15 2013) Journal Articles Purpose. To evaluate the eye-tracking–based follow-up (EBF) function in the reproducibility of the peripapillary retinal nerve fiber layer (RNFL) thickness measurements obtained with Fourier-domain optical coherence tomography (Fd-OCT). Methods. Thirty healthy subjects were imaged on an Fd-OCT device at the same visit by two examiners. Peripapillary circular scans in ... (Read Full Article)

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24. Association of Retinal Sensitivity to Integrity of Photoreceptor Inner/Outer Segment Junction in Patients with Diabetic Macular Edema Explore Ophthalmology (Mar 14 2013) Journal Articles Purpose: To evaluate the relationship between retinal sensitivity and the photoreceptor inner segment/outer segment (IS/OS) layer status in patients with diabetic macular edema (DME). Design: Cross-sectional study. Participants: Twenty-five adult patients (37 eyes) diagnosed with DME and managed at the Wilmer Eye Institute, Johns Hopkins University (Baltimore, MD ... (Read Full Article)

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