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Popular Articles
Video Case Report: Dry Age-Related Macular Degeneration
Video: David Brown, MD discusses visualizing the subtle differences in fluids related to AMD
Video Case Report: Wet Age-Related Macular Degeneration
Cirrus HD-OCT: Advanced Imaging Capabilities for Differential Diagnosis in Macular Disease
Monitoring Retinal Change in AMD Patients using Cirrus HD-OCT
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Articles in category: AMD
Subfoveal Choroidal Thickness after Ranibizumab Therapy for Neovascular Age-related Macular Degeneration: 12-Month Results
Explore OphSource (May 1 2012)
Purpose: To investigate the changes in subfoveal choroidal thickness after intravitreal injections of ranibizumab (IVRs) for neovascular age-related macular degeneration (AMD).Design: Prospective, consecutive, interventional case series.Participants: Eighty eyes (40 affected eyes with neovascular AMD and 40 unaffected fellow eyes) of 40 patients.Methods: Forty eyes with neovascular AMD ...
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Improvement of Photoreceptor Integrity and Associated Visual Outcome in Neovascular Age-Related Macular Degeneration
Explore American Journal of Ophthalmology (Apr 26 2012)
Purpose: To evaluate the association between improvement of photoreceptor integrity and visual acuity (VA) after anti–vascular endothelial growth factor (anti-VEGF) injections in neovascular age-related macular degeneration (AMD).Design: Retrospective, cross-sectional study.Methods: Eighty-seven eyes of 84 patients who were newly diagnosed with neovascular AMD and treated with anti-VEGF injections ...
(Read Full Article)
Early Simultaneous Fundus Autofluorescence and Optical Coherence Tomography Features After Pars Plana Vitrectomy for Primary Rhegmatogenous Retinal Detachment
Explore pdfs.journals.lww.com (Feb 24 2012)
Purpose: To describe fundus autofluorescence and optical coherence tomography (OCT) features of the macula after pars plana vitrectomy for rhegmatogenous retinal detachment.Methods: Thirty-three eyes of 33 consecutive patients with repaired rhegmatogenous retinal detachment with or without the involvement of the macula were prospectively investigated with simultaneous fundus autofluorescence and ...
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The Significance of Early Treatment of Exudative Age-related Macular Degeneration
Explore pdfs.journals.lww.com (Feb 24 2012)
Purpose: To determine whether the time span between initial symptoms and treatment with ranibizumab in patients with neovascular age-related macular degeneration has an effect on visual outcome.Method: In this retrospective study, 45 patients with exudative age-related macular degeneration were split into 3 groups depending on the duration of visual ...
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Relationships among Multifocal Electroretinogram Amplitude, Visual Field Sensitivity, and SD-OCT Receptor Layer Thicknesses in Patients with Retinitis Pigmentosa
Explore iovs.org (Feb 21 2012)
Purpose. To compare local functional measures, the multifocal electroretinogram (mfERG) and visual field sensitivity, with a local structural measure, spectral domain (SD) optical coherence tomography (OCT), of receptor damage in patients with retinitis pigmentosa (RP). Methods. MfERGs, visual fields, and SD-OCT scans were obtained from 10 patients with RP, ranging ...
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Detection of New-Onset Choroidal Neovascularization Using Optical Coherence Tomography: The Amd Doc Study - Corrected Proof
Explore OphSource (Jan 31 2012)
Purpose: To determine the sensitivity of time domain optical coherence tomography (OCT) in detecting conversion to neovascular age-related macular degeneration (AMD) in eyes at high risk for choroidal neovascularization (CNV), compared with detection using fluorescein angiography (FA) as the gold standard.Design: Prospective, multicenter, observational study.Participants: Individuals aged ≥50 ...
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Fixed-Interval Versus OCT-Guided Variable Dosing of Intravitreal Bevacizumab in the Management of Neovascular Age-Related Macular Degeneration: A 12-Month Randomized Prospective Study - Corrected Proof
Explore American Journal of Ophthalmology (Oct 18 2011)
Purpose: To compare the efficacy of as-needed or variable dosing of intravitreal bevacizumab to continuous fixed-interval dosing in the management of neovascular age-related macular degeneration (AMD).Design: Prospective, open-label, randomized clinical study.Methods: One hundred twenty eyes of 120 patients with treatment-naïve subfoveal neovascular AMD participated in this study at ... (Read Full Article)
Retinal and Choroidal Thickness in Early Age-Related Macular Degeneration - Corrected Proof
Explore American Journal of Ophthalmology (Aug 17 2011)
Purpose: To compare retinal thickness and choroidal thickness at increasing retinal eccentricity in individuals with early age-related macular degeneration (AMD) and in healthy controls using enhanced choroidal penetration, 3-dimensional optical coherence tomography at 1060 nm.Design: Cross-sectional study.Methods: Individuals with early AMD (n = 16; mean age, 71.6 ± 8 ... (Read Full Article)
Mentions: Drexler, Wolfgang PhD
The Role of Spectral-Domain OCT in the Diagnosis and Management of Neovascular Age-Related Macular Degeneration
Explore SLACK Journals (Aug 13 2011)
Spectral-domain optical coherence tomography (SD-OCT) has emerged as the ancillary examination of choice to assist the diagnosis and management of neovascular age-related macular degeneration (AMD). SD-OCT provides more detailed images of intraretinal, subretinal, and subretinal pigment epithelium fluid when compared to time-domain technology, leading to higher and earlier detection rates ... (Read Full Article)
Mentions: Carl Zeiss Meditec Duker, Jay S. MD New England Eye Center
Early Perfusion of a Free RPE-Choroid Graft in Patients with Exudative Macular Degeneration Can Be Imaged with Spectral Domain-OCT [Clinical Trials]
Explore iovs.org (Jul 29 2011)
Purpose. To study early flow and revascularization in a free, autologous, retinal pigment epithelium (RPE)–choroid graft. Methods. This prospective cohort study used spectral domain–optical coherence tomography (SD-OCT) after RPE–choroid graft surgery in 12 patients. This SD-OCT was combined with fluorescein angiography (FA) and indocyanine green angiography (ICGA ... (Read Full Article)
Diagnostic Evaluation of Type 2 (Classic) Choroidal Neovascularization: Optical Coherence Tomography, Indocyanine Green Angiography, and Fluorescein Angiography - Corrected Proof
Explore American Journal of Ophthalmology (Jul 10 2011)
Purpose: To evaluate the diagnostic characteristics of type 2 (classic) choroidal neovascularizations secondary to age-related macular degeneration using spectral domain-optical coherence tomography (SD OCT), indocyanine green angiography (ICGA), and fluorescein angiography (FA). (Read Full Article)
Mentions: Schmidt-Erfurth, Ursula MD Medical University of Vienna
Natural History of Drusen Morphology in Age-Related Macular Degeneration Using Spectral Domain Optical Coherence Tomography - Corrected Proof
Explore OphSource (Jul 3 2011)
To characterize the natural history of drusen using spectral-domain optical coherence tomography (SD-OCT) imaging of eyes from patients with nonexudative age-related macular degeneration (AMD). (Read Full Article)
Mentions: Cirrus HD-OCT Bascom Palmer Eye Institute Rosenfeld, Philip, MD
Retinal Pigment Epithelium Tears Secondary to Age-Related Macular Degeneration: A Simultaneous Confocal Scanning Laser Ophthalmoscopy and Spectral-Domain Optical Coherence Tomography Study [Clinical Sciences]
Explore archopht.ama-assn.org (May 9 2011)
To describe the morphology of retinal pigment epithelium (RPE) tears secondary to age-related macular degeneration by using high-resolution, spectral-domain optical coherence tomography (SD-OCT). (Read Full Article)
Intersession repeatability of optical coherence tomography measures of retinal thickness in early age-related macular degeneration
Explore Wiley Online Library (May 1 2011)
To determine the intersession repeatability of Stratus optical coherence tomography (OCT) measures of retinal thickness in patients with age-related macular degeneration (AMD).
(Read Full Article)
Mentions: Stratus OCT
Bevacizumab versus Ranibizumab — The Verdict
Explore The New England Journal of Medicine (Apr 28 2011)
For 5 years, patients and clinicians have wrestled with the choice between two drugs for the treatment of neovascular age-related macular degeneration (AMD), a common cause of irreversible blindness among the elderly worldwide. (Read Full Article)
Mentions: Bascom Palmer Eye Institute Genentech
Spectral Domain Optical Coherence Tomography Imaging of Drusen in Nonexudative Age-Related Macular Degeneration - Corrected Proof
Explore OphSource (Mar 8 2011)
To measure drusen area and volume in eyes with nonexudative age-related macular degeneration (AMD) using spectral domain optical coherence tomography imaging (Read Full Article)
Mentions: Bascom Palmer Eye Institute Puliafito, Carmen A. MD Rosenfeld, Philip, MD
Is quantitative spectral-domain superior to time-domain optical coherence tomography (OCT) in eyes with age-related macular degeneration?
Explore Wiley Online Library (Mar 4 2011)
The aim of this study was to determine the variability of macular map measurements, for two generations of optical coherence tomography (OCT) instruments, in eyes with wet age related macular degeneration (AMD) and low visual acuity. (Read Full Article)
Mentions: Cirrus HD-OCT Stratus OCT
Optical Coherence Tomography and Autofluorescence Findings in Areas with Geographic Atrophy Due to Age-Related Macular Degeneration [Clinical Trials]
To analyze outer retinal changes within the atrophic lesion in patients with geographic atrophy (GA) secondary to age-related macular degeneration. (Read Full Article)
Choroidal Thickness in Polypoidal Choroidal Vasculopathy and Exudative Age-Related Macular Degeneration - Corrected Proof
Explore Ophthalmology (Jan 5 2011)
To compare choroidal thickness between eyes with polypoidal choroidal vasculopathy (PCV) and eyes with age-related macular degeneration (AMD). (Read Full Article)
Spectral domain optical coherence tomography features of multiple subfoveal retinal pigment epithelial tears after intravitreal bevacizumab
Explore Indian Journal of Ophthalmology (IJO) (Dec 15 2010)
Retinal pigment epithelial (RPE) tear has been described to occur spontaneously, after laser photocoagulation and in recent times, after intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents. In the latter case, the rapid contraction of the choroidal vascular membrane underneath a serous RPE detachment is believed to be the ...
(Read Full Article)
Mentions: Stratus OCT
Vitreomacular Interface in Typical Exudative Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy
Explore Ophthalmology (Nov 21 2010)
To investigate the association in Japanese between posterior vitreous attachment and the pathologies of typical age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV), 2 major forms of exudative AMD. (Read Full Article)
Progression of Geographic Atrophy in Age-Related Macular Degeneration Imaged with Spectral Domain Optical Coherence Tomography
Explore Ophthalmology (Oct 28 2010)
To determine the area and enlargement rate (ER) of geographic atrophy (GA) in patients with age-related macular degeneration (AMD) using the spectral domain optical coherence tomography (SD-OCT) fundus image. (Read Full Article)
Mentions: Carl Zeiss Meditec Cirrus HD-OCT Bascom Palmer Eye Institute
Quantitative Comparison of Drusen Segmented on SD-OCT versus Drusen Delineated on Color Fundus Photographs [Clinical Trials]
Explore iovs.org (Sep 28 2010)
Spectral domain–optical coherence tomography (SD-OCT) may be useful for efficient measurement of drusen in patients with age-related macular degeneration (AMD). Areas identified as drusen from semiautomated segmentation of drusen on SD-OCT were compared to those identified from review of digital color fundus photographs (CFPs). (Read Full Article)
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