Articles from American Journal of Ophthalmology

1. Near-infrared and Short-wavelength Autofluorescence in Resolved Central Serous Chorioretinopathy: Association With Outer Retinal Layer Abnormalities Explore American Journal of Ophthalmology (Apr 17 2013) Journal Articles Purpose: To evaluate the correlation between changes in fundus autofluorescence (AF) measured using 2 different sources (near-infrared fundus autofluorescence from melanin and short-wavelength fundus autofluorescence from lipofuscin) with changes in spectral-domain optical coherence tomography (SD OCT) and fluorescein angiography in resolved central serous chorioretinopathy (CSC).Design: Retrospective, observational case study ... (Read Full Article)

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2. Foveal Thickness in Healthy Fellow Eyes of Patients With Unilateral Macular Holes Explore American Journal of Ophthalmology (Mar 28 2013) Journal Articles Purpose: To compare the morphologic parameters of ophthalmoscopically and tomographically normal foveae of the fellow eyes of patients with a unilateral macular hole (MH), other unilateral retinal diseases, and healthy eyes.Design: Observational, cross-sectional study.Methods: Of the 849 subjects studied, 183 eyes were excluded because they had an abnormal ... (Read Full Article)

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3. Morphologic Characteristics of Optic Nerve Head Drusen on Spectral-Domain Optical Coherence Tomography Explore American Journal of Ophthalmology (Mar 19 2013) Journal Articles Purpose: To evaluate the morphologic characteristics of optic nerve head drusen.Design: Retrospective case series.Methods: Setting: Institutional (Seoul National University Bundang Hospital). Patients: Sixty-one patients with optic nerve head drusen. Observation procedure: Visible and buried optic nerve head drusen were identified using funduscopy, whereas homogenous and nonhomogenous optic nerve ... (Read Full Article)

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4. Characterization of Ischemic Index Using Ultra-widefield Fluorescein Angiography in Patients With Focal and Diffuse Recalcitrant Diabetic Macular Edema Explore American Journal of Ophthalmology (Feb 27 2013) Journal Articles Purpose: To explore the association of angiographic nonperfusion in focal and diffuse recalcitrant diabetic macular edema (DME) in diabetic retinopathy (DR).Design: A retrospective, observational case series of patients with the diagnosis of recalcitrant DME for at least 2 years placed into 1 of 4 cohorts based on the degree ... (Read Full Article)

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5. Comparison of Cone Pathologic Changes in Idiopathic Macular Telangiectasia Types 1 and 2 Using Adaptive Optics Scanning Laser Ophthalmoscopy Explore American Journal of Ophthalmology (Feb 25 2013) Journal Articles Purpose: To compare pathologic changes in the photoreceptors of eyes with idiopathic macular telangiectasia types 1 and 2 using adaptive optics scanning laser ophthalmoscopy (AO-SLO).Design: Prospective cross-sectional study.Methods: Eleven eyes with idiopathic macular telangiectasia type 1, 14 eyes with type 2, and 10 normal eyes underwent a full ... (Read Full Article)

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6. Peripapillary Scleral Deformation and Retinal Nerve Fiber Damage in High Myopia Assessed With Swept-Source Optical Coherence Tomography Explore American Journal of Ophthalmology (Feb 24 2013) Journal Articles Purpose: To study peripapillary morphologic changes in highly myopic eyes using swept-source optical coherence tomography at a longer wavelength.Design: Prospective cross-sectional study.Methods: Peripapillary regions of 196 eyes of 107 patients with high myopia (refractive error, 26.0 mm) were analyzed quantitatively and qualitatively with an swept-source optical coherence ... (Read Full Article)

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7. Imaging Retinal Pigment Epithelial Proliferation Secondary to PASCAL Photocoagulation In Vivo by Polarization-sensitive Optical Coherence Tomography Explore American Journal of Ophthalmology (Feb 24 2013) Journal Articles Purpose: To image the retinal pigment epithelium (RPE) after macular laser and to monitor healing responses over time in vivo in patients with diabetic maculopathy using polarization-sensitive optical coherence tomography (OCT).Design: Prospective, nonrandomized clinical trial.Methods: In this single-center trial (Department of Ophthalmology and Optometry, Medical University of Vienna ... (Read Full Article)

   Comment Mentions:   Schmidt-Erfurth, Ursula MD   Medical University of Vienna

8. Color-Code Agreement Among Stratus, Cirrus, and Spectralis Optical Coherence Tomography in Relapsing-Remitting Multiple Sclerosis With and Without Prior Optic Neuritis Explore American Journal of Ophthalmology (Feb 10 2013) Journal Articles Purpose: To evaluate the agreement of retinal nerve fiber layer (RNFL) color codes among Stratus, Cirrus, and Spectralis optical coherence tomography (OCT) in patients with relapsing-remitting multiple sclerosis.Design: Prospective cohort study.Methods: In 140 eyes from 70 patients having relapsing-remitting multiple sclerosis from January 2011 to September 2011, peripapillary ... (Read Full Article)

   Comment Mentions:   Cirrus HD-OCT   Stratus OCT

9. High-Resolution Imaging of Retinal Nerve Fiber Bundles in Glaucoma Using Adaptive Optics Scanning Laser Ophthalmoscopy Explore American Journal of Ophthalmology (Jan 23 2013) Journal Articles Purpose: To detect pathologic changes in retinal nerve fiber bundles in glaucomatous eyes seen on images obtained by adaptive optics (AO) scanning laser ophthalmoscopy (AO SLO).Design: Prospective cross-sectional study.Methods: Twenty-eight eyes of 28 patients with open-angle glaucoma and 21 normal eyes of 21 volunteer subjects underwent a full ... (Read Full Article)

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10. Retroprosthetic Membrane and Risk of Sterile Keratolysis in Patients With Type I Boston Keratoprosthesis Explore American Journal of Ophthalmology (Jan 23 2013) Journal Articles Purpose: To evaluate whether retro-backplate retroprosthetic membrane is correlated with risk of melt in patients with a type I Boston Keratoprosthesis (KPro).Design: Retrospective, observational case series.Methods: Study of 50 eyes of 47 patients with type I Boston KPro and postoperative anterior segment optical coherence tomography (AS OCT) imaging ... (Read Full Article)

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11. Comparison of Clinical Characteristics Between Korean and Western Normal-Tension Glaucoma Patients Explore American Journal of Ophthalmology (Jan 23 2013) Journal Articles Purpose: To detect potential differences in the phenotypes between Western normal-tension glaucoma (NTG) and Korean NTG.Design: A retrospective, cross-sectional study.Methods: One hundred eighty-four NTG eyes of 71 patients of the Jules Stein Eye Institute, University of California, Los Angeles, and 113 patients of the Seoul National University Hospital ... (Read Full Article)

    Comment Mentions:   Stratus OCT

12. Angiographic and Optical Coherence Tomography Characteristics of Recent Myopic Choroidal Neovascularization Explore American Journal of Ophthalmology (Jan 23 2013) Journal Articles Purpose: To analyze the contribution of fluorescein angiography (FA) and spectral-domain optical coherence tomography (SD OCT) to the diagnosis of recent choroidal neovascularization (CNV) associated with high myopia.Design: Retrospective, observational case series.Methods: Ninety eyes of 73 highly myopic patients (refractive error ≥−6 diopters) with CNV in 1 or ... (Read Full Article)

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13. Thinner Choroid and Greater Drusen Extent in Retinal Angiomatous Proliferation Than in Typical Exudative Age-Related Macular Degeneration Explore American Journal of Ophthalmology (Jan 13 2013) Journal Articles Purpose: To compare choroidal thickness and extent and density of drusen between eyes with typical exudative age-related macular degeneration (AMD) and eyes with retinal angiomatous proliferation (RAP).Design: Observational case series.Methods: Twenty-four eyes with typical exudative AMD and 20 eyes with RAP were included. Subfoveal choroidal thickness was measured ... (Read Full Article)

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14. Predictive Value of Spectral-Domain Optical Coherence Tomography Features in Assessment of Visual Prognosis in Eyes With Neovascular Age-Related Macular Degeneration Treated with Ranibizumab Explore American Journal of Ophthalmology (Jan 13 2013) Journal Articles Purpose: To determine whether pretreatment (baseline) optical coherence tomography (OCT) features can be used as predictors of visual acuity outcome at 12 months in eyes with neovascular age-related macular degeneration treated with intravitreal ranibizumab and to assess whether baseline OCT features can predict a change in visual acuity from baseline ... (Read Full Article)

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15. Tear Meniscus Evaluation by Anterior Segment Swept-Source Optical Coherence Tomography Explore American Journal of Ophthalmology (Jan 13 2013) Journal Articles Purpose: To investigate the repeatability of tear meniscus measurements using anterior segment swept-source optical coherence tomography (OCT) and the relationship of tear meniscus measurements with tear film breakup time and Schirmer test results.Design: Prospective, observational, cross-sectional study.Methods: We enrolled 26 healthy subjects (26 eyes; 20 men and 6 ... (Read Full Article)

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16. Macular Pseudoholes with Lamellar Cleavage of Their Edge Remain Pseudoholes Explore American Journal of Ophthalmology (Jan 9 2013) Journal Articles Purpose: To reappraise macular pseudohole characteristics using spectral-domain optical coherence tomography (OCT) and characteristics and postoperative outcomes of macular pseudoholes.Design: Retrospective, observational case series.Methods: In this institutional study, 54 eyes with macular pseudohole were selected among 369 patients examined for an epiretinal membrane (ERM) by Cirrus spectral-domain OCT ... (Read Full Article)

    Comment Mentions:   Carl Zeiss Meditec   Cirrus HD-OCT

17. Combined Depth Imaging Technique on Spectral-Domain Optical Coherence Tomography Explore American Journal of Ophthalmology (Dec 17 2012) Journal Articles Purpose: To describe a technique to obtain combined images of vitreoretinal and choroidal structures using spectral-domain (SD) optical coherence tomography (OCT) and to evaluate applicability in normal eyes and limitations in eyes with cataract.Design: Prospective, observational case series.Methods: Three different foveal scans, including conventional SD OCT, enhanced depth ... (Read Full Article)

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18. Ocular Biometry in the Subtypes of Angle Closure: An Anterior Segment Optical Coherence Tomography Study Explore American Journal of Ophthalmology (Dec 12 2012) Journal Articles Purpose: To evaluate ocular biometric parameters in different subtypes of angle-closure disease in the Iranian population and compare them with normal eyes.Design: Prospective, cross-sectional.Methods: In this clinic-based study, 189 eyes of 154 patients consisting of 40 acute angle-closure glaucoma (AACG) eyes, 40 fellow eyes of AACG, 42 chronic ... (Read Full Article)

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19. Visual Outcome in Isoametropic Amblyopic Children With High Hyperopia and the Effect of Therapy on Retinal Thickness Explore American Journal of Ophthalmology (Dec 6 2012) Journal Articles Purpose: To assess correlations between associated factors and treatment outcome of isoametropic amblyopia attributable to high hyperopia in children and to evaluate changes in retinal thickness during amblyopic treatment.Design: Retrospective (visual outcome) and prospective (retinal thickness) study.Methods: Isoametropic (spherical equivalent ≥5.00 diopters in both eyes) amblyopic subjects ... (Read Full Article)

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20. Capsular Adhesion to Intraocular Lens in Highly Myopic Eyes Evaluated In Vivo Using Ultralong-scan-depth Optical Coherence Tomography - Corrected Proof Explore American Journal of Ophthalmology (Dec 3 2012) Journal Articles Purpose: To evaluate the in vivo capsular apposition to the intraocular lens (IOL) in subjects with high myopia by ultralong-scan-depth optical coherence tomography (OCT).Design: Prospective observational case series.Methods: Forty eyes from 40 cataract patients scheduled for phacoemulsification surgery at the Affiliated Eye Hospital, Wenzhou Medical College were studied ... (Read Full Article)

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21. Normative Reference Ranges for the Retinal Nerve Fiber Layer, Macula, and Retinal Layer Thicknesses in Children Explore American Journal of Ophthalmology (Nov 4 2012) Journal Articles Purpose: To establish a normative database of peripapillary retinal nerve fiber layer (RNFL) thickness, macular thickness, and retinal layer thickness in healthy North American children, using spectral-domain optical coherence tomography (SD-OCT).Design: Prospective cross-sectional study.Methods: This institutional study enrolled 83 healthy children (aged 5-15 years) as volunteer research subjects ... (Read Full Article)

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22. Computerized Assessment of Intraretinal and Subretinal Fluid Regions in Spectral-Domain Optical Coherence Tomography Images of the Retina Explore American Journal of Ophthalmology (Oct 28 2012) Journal Articles Purpose: To evaluate a new computerized segmentation technique for the quantification of intraretinal and subretinal fluid in spectral-domain optical coherence tomography (SD OCT) images of the retina.Design: Prospective, cross-sectional study.Methods: Thirty-seven B-scan images of 37 patients with exudative age-related macular degeneration were chosen randomly from SD OCT volume ... (Read Full Article)

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23. Increasing Prevalence and Severity of Conjunctivochalasis With Aging Detected by Anterior Segment Optical Coherence Tomography Explore American Journal of Ophthalmology (Oct 1 2012) Journal Articles Purpose: To evaluate the impact of aging on conjunctivochalasis in an objective manner using anterior segment optical coherence tomography.Design: Prospective clinical trial.Methods: Sixty eyes of 30 healthy volunteers (15 men, 15 women; age range, 24-75 years) without any ophthalmic diseases were recruited for the study. Subjects were organized ... (Read Full Article)

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24. Retinal Nerve Fiber Layer Atrophy Is Associated With Visual Field Loss Over Time in Glaucoma Suspect and Glaucomatous Eyes Explore American Journal of Ophthalmology (Oct 1 2012) Journal Articles Purpose: To compare prospectively detection of progressive retinal nerve fiber layer thickness (RNFL) atrophy identified using time-domain optical coherence tomography with visual field progression using standard automated perimetry in glaucoma suspect and preperimetric glaucoma patients or perimetric glaucoma patients.Design: Prospective, longitudinal clinical trial.Methods: Eligible eyes with 2 years ... (Read Full Article)

    Comment Mentions:   Schuman, Joel MD   Bascom Palmer Eye Institute   University of Pittsburgh

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