Articles from OphSource

1. Choroidal Thickness in Both Eyes of Patients with Unilateral Idiopathic Macular Hole Explore OphSource (Aug 12 2012) Journal Articles Purpose: To compare the choroidal thickness in the macular area in eyes with an idiopathic macular hole (IMH) with that of unaffected fellow eyes and eyes of healthy controls. Design: A cross-sectional study. Participants: Fifty patients with unilateral IMH and 50 healthy controls. Methods: Enhanced depth imaging was obtained by ... (Read Full Article)

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2. Montage Images of Spectral-Domain Optical Coherence Tomography in Eyes with Idiopathic Macular Holes Explore OphSource (Aug 12 2012) Journal Articles Purpose: To describe the morphologic and anatomic relationships at the vitreoretinal interface, from the macula into the periphery, in patients with idiopathic macular hole. Montaged images of posterior and peripheral spectral-domain (SD) optical coherence tomography (OCT) studies were used to describe the anatomic vitreoretinal relationships. Design: Prospective, consecutive, observational case ... (Read Full Article)

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3. Diagnosing Preperimetric Glaucoma with Spectral Domain Optical Coherence Tomography Explore OphSource (Aug 7 2012) Journal Articles Purpose: To evaluate the diagnostic accuracy of spectral domain optical coherence tomography (SD-OCT) for detection of preperimetric glaucoma and compare it with the performance of confocal scanning laser ophthalmoscopy (CSLO). Design: Cohort study. Participants: A cohort of 134 eyes of 88 glaucoma suspects based on the appearance of the optic ... (Read Full Article)

   Comment Mentions:   University of California at San Diego

4. Ability and Reproducibility of Fourier-Domain Optical Coherence Tomography to Detect Retinal Nerve Fiber Layer Atrophy in Parkinson's Disease Explore OphSource (Jun 28 2012) Journal Articles , Neuro-Ophthalmology Purpose: To evaluate and compare the ability of 3 protocols of Fourier-domain optical coherence tomography (OCT) to detect retinal thinning and retinal nerve fiber layer (RNFL) atrophy in patients with Parkinson's disease (PD) compared with healthy subjects. To test the intrasession reproducibility of RNFL thickness measurements in patients with ... (Read Full Article)

   Comment Mentions:   Cirrus HD-OCT

5. Visualization of the Conventional Outflow Pathway in the Living Human Eye Explore OphSource (Jun 7 2012) Journal Articles Purpose: We sought to visualize the aqueous outflow system in 3 dimensions (3D) in living human eyes, and to investigate the use of commercially available spectral-domain optical coherence tomographic (SD-OCT) systems for this purpose.Design: Prospective, observational study.Participants: One randomly determined eye in each of 6 normal healthy subjects ... (Read Full Article)

   Comment Mentions:   Cirrus HD-OCT   Schuman, Joel MD   University of Pittsburgh

6. Retinal Nerve Fiber Layer Imaging with Spectral-domain Optical Coherence Tomography: Patterns of Retinal Nerve Fiber Layer Progression Explore OphSource (Jun 5 2012) Journal Articles Objective: To examine the use of the retinal nerve fiber layer (RNFL) thickness map generated by a spectral-domain optical coherence tomography (OCT) to detect RNFL progression and identify the pattern of progressive changes of RNFL defects in glaucoma.Design: Prospective, longitudinal study.Participants: One hundred eighty-six eyes of 103 glaucoma ... (Read Full Article)

   Comment Mentions:   Carl Zeiss Meditec   Cirrus HD-OCT   University of California at San Diego

7. Visual Acuity, Optical Components, and Macular Abnormalities in Patients with a History of Retinopathy of Prematurity Explore OphSource (May 10 2012) Journal Articles Purpose: To examine the optical components and spectral-domain optical coherence tomography (OCT) findings in children with a history of retinopathy of prematurity (ROP) and to identify any associations between the OCT findings and the visual acuities of the patients.Design: Prospective, case-controlled study.Participants and Controls: Children who were between ... (Read Full Article)

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8. Optic Disc Imaging with Spectral-Domain Optical Coherence Tomography: Variability and Agreement Study with Heidelberg Retinal Tomograph Explore OphSource (May 8 2012) Journal Articles Objective: To evaluate the agreement of optic disc measurements obtained with the Cirrus high-density optical coherence tomography (HD-OCT) and the Heidelberg retina tomograph (HRT) and compare the intervisit, test–retest variability between the instruments.Design: Prospective, cross-sectional study.Participants: Two hundred seven subjects (109 glaucoma and 98 normal subjects).Methods ... (Read Full Article)

   Comment Mentions:   Cirrus HD-OCT

9. Subfoveal Choroidal Thickness after Ranibizumab Therapy for Neovascular Age-related Macular Degeneration: 12-Month Results Explore OphSource (May 1 2012) Journal Articles , AMD Purpose: To investigate the changes in subfoveal choroidal thickness after intravitreal injections of ranibizumab (IVRs) for neovascular age-related macular degeneration (AMD).Design: Prospective, consecutive, interventional case series.Participants: Eighty eyes (40 affected eyes with neovascular AMD and 40 unaffected fellow eyes) of 40 patients.Methods: Forty eyes with neovascular AMD ... (Read Full Article)

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10. Assessment of Macular Choroidal Thickness by Optical Coherence Tomography and Angiographic Changes in Central Serous Chorioretinopathy Explore OphSource (Apr 22 2012) Journal Articles Objective: To investigate the relationship between macular choroidal thickness measured by high-penetrating swept-source optical coherence tomography (SS-OCT) and angiographic findings in central serous chorioretinopathy (CSC).Design: Prospective cross-sectional case series.Participants and Controls: Thirty-four patients with CSC (44 eyes) and 17 volunteer subjects (17 normal eyes).Methods: All subjects underwent ... (Read Full Article)

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11. Reversal of Lamina Cribrosa Displacement and Thickness after Trabeculectomy in Glaucoma Explore OphSource (Mar 29 2012) Journal Articles Purpose: To investigate the response of the lamina cribrosa (LC) and prelaminar tissue to glaucoma surgery using spectral-domain optical coherence tomography (SD-OCT) and to determine the factors influencing such responses.Design: Observational case series.Participants: Thirty-five eyes of 35 primary open-angle glaucoma patients who underwent trabeculectomy.Methods: Patients were imaged ... (Read Full Article)

    Comment Mentions:   University of California at San Diego   Weinreb, Robert N. MD

12. Hyporeflective Wedge-Shaped Band in Geographic Atrophy Secondary to Age-Related Macular Degeneration: An Underreported Finding Explore OphSource (Mar 21 2012) Journal Articles Objective: To describe and interpret the frequently observed spectral-domain optical coherence tomography (SD-OCT) finding of a marked hyporeflective wedge-shaped structure at the boundaries of the areas of atrophy.Design: A prospective, longitudinal follow-up study.Participants: Consecutive patients (n = 71) 50 years of age and older with geographic atrophy (GA) secondary ... (Read Full Article)

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13. Determinants of Anterior Chamber Depth: The Singapore Chinese Eye Study Explore OphSource (Mar 13 2012) Journal Articles Purpose: Recent advances in anterior segment imaging have enabled the measurement of novel ocular biometric parameters, such as lens vault (LV), posterior corneal arc length (PCAL), and iris area. The aims of this study were to identify the determinants of anterior chamber depth (ACD) and to ascertain the relative importance ... (Read Full Article)

    Comment Mentions:   Carl Zeiss Meditec

14. Changes in Anterior Segment Morphology after Laser Peripheral Iridotomy: An Anterior Segment Optical Coherence Tomography Study - Corrected Proof Explore OphSource (Mar 11 2012) Journal Articles , Anterior Segment Purpose: Novel anterior segment optical coherence tomography (ASOCT) parameters associated with angle closure include anterior chamber area (ACA), anterior chamber volume (ACV), anterior chamber width (ACW), lens vault (LV), iris thickness (IT), iris area (I-area), and iris curvature (I-curv). We aimed to investigate changes in these parameters after laser peripheral ... (Read Full Article)

    Comment Mentions:   Carl Zeiss Meditec   Visante omni

15. Ganglion Cell Loss in Relation to Visual Disability in Multiple Sclerosis Explore OphSource (Feb 23 2012) Journal Articles , Neuro-Ophthalmology Purpose: We used high-resolution spectral-domain optical coherence tomography (SD-OCT) with retinal segmentation to determine how ganglion cell loss relates to history of acute optic neuritis (ON), retinal nerve fiber layer (RNFL) thinning, visual function, and vision-related quality of life (QOL) in multiple sclerosis (MS).Design: Cross-sectional study.Participants: A convenience ... (Read Full Article)

    Comment Mentions:   Schuman, Joel MD   University of Pittsburgh

16. Glaucoma Diagnostic Accuracy of Ganglion Cell–Inner Plexiform Layer Thickness: Comparison with Nerve Fiber Layer and Optic Nerve Head Explore OphSource (Feb 23 2012) Journal Articles Purpose: To determine the diagnostic performance of macular ganglion cell–inner plexiform layer (GCIPL) thickness measured with the Cirrus high-definition optical coherence tomography (HD-OCT) ganglion cell analysis (GCA) algorithm (Carl Zeiss Meditec, Dublin, CA) to discriminate normal eyes and eyes with early glaucoma and to compare it with that of ... (Read Full Article)

    Comment Mentions:   Carl Zeiss Meditec   Cirrus HD-OCT   Bascom Palmer Eye Institute

17. Detection of New-Onset Choroidal Neovascularization Using Optical Coherence Tomography: The Amd Doc Study - Corrected Proof Explore OphSource (Jan 31 2012) Journal Articles , AMD Purpose: To determine the sensitivity of time domain optical coherence tomography (OCT) in detecting conversion to neovascular age-related macular degeneration (AMD) in eyes at high risk for choroidal neovascularization (CNV), compared with detection using fluorescein angiography (FA) as the gold standard.Design: Prospective, multicenter, observational study.Participants: Individuals aged ≥50 ... (Read Full Article)

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18. Enhanced Depth Imaging Optical Coherence Tomography of Choroidal Nevus in 104 Cases Explore OphSource (Jan 30 2012) Journal Articles , Retina Purpose: To describe the characteristics of choroidal nevus using the enhanced depth imaging (EDI) feature of spectral-domain optical coherence tomography (OCT).Design: Retrospective, observational case series.Participants: One hundred four eyes with choroidal nevus.Methods: Spectral-domain EDI OCT was performed with a Heidelberg Spectralis HRA+OCT (Heidelberg Engineering, Heidelberg, Germany ... (Read Full Article)

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19. Retinal Nerve Fiber Layer Imaging with Spectral-Domain Optical Coherence Tomography: A Prospective Analysis of Age-Related Loss - Corrected Proof Explore OphSource (Jan 18 2012) Journal Articles Objective: To investigate age-related changes of the retinal nerve fiber layer (RNFL) imaged by a spectral-domain optical coherence tomography (OCT). Design: Prospective, cross-sectional, and longitudinal studies. Participants: One hundred normal individuals were recruited for cross-sectional analysis, 35 of whom were randomly selected for longitudinal analysis. Methods: The circumpapillary average and ... (Read Full Article)

    Comment Mentions:   Cirrus HD-OCT   University of California at San Diego   Weinreb, Robert N. MD

20. Optic Disc Margin Anatomy in Patients with Glaucoma and Normal Controls with Spectral Domain Optical Coherence Tomography Explore OphSource (Jan 3 2012) Journal Articles , Glaucoma Objective: To characterize optic nerve head (ONH) anatomy related to the clinical optic disc margin with spectral domain-optical coherence tomography (SD-OCT). Design: Cross-sectional study. Participants: Patients with open-angle glaucoma with focal, diffuse, and sclerotic optic disc damage, and age-matched normal controls. Methods: High-resolution radial SD-OCT B-scans centered on the ONH ... (Read Full Article)

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21. Progression Detection Capability of Macular Thickness in Advanced Glaucomatous Eyes Explore OphSource (Dec 18 2011) Journal Articles , Glaucoma Purpose: To evaluate the progression rate of macular and circumpapillary retinal nerve fiber layer (RNFL) thickness in advanced glaucomatous eyes using spectral domain optical coherence tomography (Cirrus HD-OCT, Carl Zeiss Meditec, Dublin, CA). Design: Longitudinal, observational study. Participants: A total of 98 eyes of 98 patients with advanced glaucoma (visual ... (Read Full Article)

    Comment Mentions:   Carl Zeiss Meditec   Cirrus HD-OCT

22. Retinal Structure, Function, and Molecular Pathologic Features in Gyrate Atrophy Explore OphSource (Dec 18 2011) Journal Articles , Retina Purpose: To describe phenotypic variability and to report novel mutational data in patients with gyrate atrophy. Design: Retrospective case series. Participants: Seven unrelated patients (10 to 52 years of age) with clinical and biochemical evidence of gyrate atrophy. Methods: Detailed ophthalmologic examination, fundus photography, fundus autofluorescence (FAF) imaging, spectral-domain optical ... (Read Full Article)

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23. Ultra-High Resolution Optical Coherence Tomography for Differentiation of Ocular Surface Squamous Neoplasia and Pterygia Explore OphSource (Dec 8 2011) Journal Articles , Retina Objective: To assess the use of an ultra–high-resolution (UHR) optical coherence tomography (OCT) as an adjuvant diagnostic tool in distinguishing ocular surface squamous neoplasia (OSSN) and pterygia. Design: Prospective case series. Participants: Thirty-four eyes of 34 patients with conjunctival lesions clinically suspicious for OSSN or pterygia. Methods: All patients ... (Read Full Article)

    Comment Mentions:   Bascom Palmer Eye Institute

24. Determinants of Angle Width in Chinese Singaporeans Explore OphSource (Nov 24 2011) Journal Articles , Anterior Segment Purpose: To investigate determinants of angle width and derive mathematic models to best predict angle width.Design: Population-based, cross-sectional study.Participants: A total of 1067 Chinese subjects aged ≥40 years.Methods: Participants underwent gonioscopy, A-scan biometry, and imaging by anterior segment optical coherence tomography (ASOCT, Carl Zeiss Meditec, Dublin, CA ... (Read Full Article)

    Comment Mentions:   Carl Zeiss Meditec

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